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Liza Soberano as Serena "Sese" Marchesa
A beautiful and determined young girl raised by an elite Italian family. She longs for a simple life despite her well-heeled upbringing. Family pressure drives her to hie off to the Philippines in search of herself and her real parents. She finds romance along the way with the crude but kind-hearted Tenten.
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Enrique Gil as Simon Vicente "Tenten" Ibarra
An ordinary boy from Manila who was adopted by the orphanage’s cook. Already taking on unconventional jobs to help support his foster family, he is drawn to work as a male escort when his adoptive father suffers a stroke. A clumsy proposition leads him to meet Serena.